The Medical Reserve Corps (MRC) is a national network of volunteers, organized locally into MRC units dedicated to improving the health and safety of their communities. MRC units engage both medical and non-medical volunteers to strengthen public health, improve emergency response capabilities, and build community resiliency. The Jackson County, Illinois MRC is housed in the Jackson County Health Department (JCHD). The JCHD is partnering with the CRHSSD in the SIU School of Medicine (SOM) to develop an SIU branch (hereafter called SIU MRC) of the Jackson County MRC (JC*MRC) comprised of students, faculty, and staff. The SIU MRC volunteers participate in JC*MRC outreach activities, volunteer trainings, and disaster drills and exercises. The SIU SOM CRHSSD service area includes 22 counties in southern Illinois. Along with enhancing the capacity of the JC*MRC, SIU MRC volunteers will be encouraged to develop innovative projects that address the health needs of the communities within the SIU School of Medicine’s southern service area. The SIU MRC project is overseen by the CRHSSD and volunteer activities are coordinated each semester by SIU Medical/Dental Education Preparatory (MEDPREP) MPH practicum students.